A Case of Neuromyelitis Optica Spectrum Disorder Presenting as Area Postrema Syndrome with Posterior Reversible Encephalopathy Syndrome-like Feature
Dong Yeop Kim, MD, Jin Myoung Seok, MD, Hye Lim Lee, MD, Eun Bin Cho, MD, Hye-Jin Cho, MD, Byoung Joon Kim, MD, PhD, Ju-Hong Min, MD, PhD
Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
With the discovery of anti-aquaporin-4 antibody (AQP4-Ab), several clinical and radiological features
beyond optic nerve and spinal cord were described in neuromyelitis optica (NMO). Area postrema
syndrome was known to be a characteristic feature of NMO, and the association between posterior
reversible encephalopathy syndrome (PRES) and NMO was reported with the pathogenic role
of AQP4-Ab. We report a case of NMO spectrum disorder (NMOSD), initially presented with concurrent
area postrema syndrome and PRES-like feature.
Journal of Multiple Sclerosis 7(2):55-58, 2016