Department of Neurology, Korea University Medical Center, Seoul, Korea
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system. The
clinical course of MS is variable case by case. Patients with low levels of disability after a course of
10 or 15 years may be considered benign MS. In the past, the level of disability was determined by
Expanded Disability Status Scale, so non-motor symptoms were less reflected. At the last decade,
the studies of non-motor symptoms and magnetic resonance image suggest the need of a new
definition. In the future, through the long term studies about neuropsychological test and magnetic
resonance image, the truly benign multiple sclerosis may be determined.
Journal of Multiple Sclerosis 3(1):6-12, 2012
keyword : Benign multiple sclerosis, Neuropsychological test, Magnetic resonance image