Journal of Multiple Sclerosis and Neuroimmunology 12(1):6-9, 2021
Recurrent Fever and Menigismus as a Manifestation of Myelin Oligodendrocyte Glycoprotein Antibody Disease
Tae-Jin Song, MD, PhD, Jee-Eun Kim, MD, PhD
Department of Neurology, College of Medicine, Ewha Womans University, Seoul, Korea
Isolated meningismus is a rare presentation in both seropositive and seronegative neuromyelitis
optica spectrum disorder (NMOSD). Here, we present a case with recurrent fever and
meningismus with anti-myelin oligodendrocyte glycoprotein (MOG) antibodies who did
not precede to other demyelinating manifestations and showed excellent response to highdose steroid treatment. This case reinforces that isolated meningismus mimicking recurrent
meningitis can occur as a direct clinical phenotype of MOG antibody disease rather than
antecedent infection triggering further demyelinating attack.
Journal of Multiple Sclerosis and Neuroimmunology 12(1):6-9, 2021
