Journal of Multiple Sclerosis and Neuroimmunology 11(2):45-52, 2020
Pregnancy in Woman with Multiple Sclerosis
Je-Young Shin, MD, Suk-Won Ahn, MD, PhDa
Department of Neurology, Seoul National University Hospital, Seoul, Korea Department of Neurology, Chung-Ang University Hospital, Seoul, Korea
Pregnancy is a major concern for many patients with multiple sclerosis (MS), who are typically
young adults at a 3:1 female predominance. Through pre-conception, pregnancy, and postpartum periods, there is need for disease control management to decrease chances of MS
relapses while avoiding potential risks to mother and fetus. However, pregnancy is not always
compatible with the available highly effective MS treatments. This review provides the impacts
on outcomes and on disease activity, anesthesia, and management of relapse during pregnancy
and breastfeeding. Furthermore, available disease-modifying treatment is discussed to support
the strategy after conception, as it is related to decreased risk of MS relapses during pregnancy
and postpartum periods.
Journal of Multiple Sclerosis and Neuroimmunology 11(2):45-52, 2020
