Sudden Onset Left Visual Field Defect in a Patient with Progressive Multifocal Leukoencephalopathy
So-Hyun Park, MD, Jeong-Min Kim, MD, PhD, Jin-Won Chung, MD, PhD1, Suk-Won Ahn, MD, PhD
Departments of Neurology and 1Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea
We report a case of progressive multifocal leukoencephalopathy who presented with sudden onset
visual field defect. A 41-year-old man complained of sudden onset left-sided visual defect and
dizziness. Brain MRI disclosed multiple high signal intensity lesions involving bilateral parieto-occipital
lobes and corpus callosum with positive serum human immunodeficiency virus antibody. With an
impression of progressive multifocal leukoencephalopathy, we initiated highly active antiretroviral
therapy, but the patient's clinical course worsened to near total blindness.
Journal of Multiple Sclerosis 9(2):28-30, 2018
keyword : Progressive multifocal leukoencephalopathy, John Cunningham virus, Human immunodeficiency virus