A Case of Combined Neuromyelitis Optica Spectrum Disorder and Demyelinating Neuropathy
Sung Joo Park, MD, Jung-Hwan Oh, MD, Sa-Yoon Kang, MD
Department of Neurology, Jeju National University School of Medicine, Jeju, Korea
Neuromyelitis optica spectrum disorder (NMOSD) is characterized by transverse myelitis or optic
neuritis with anti-aquaporin 4 antibodies. Concurrent peripheral neuropathy is rare in NMOSD. We
present the case of a patient with NMOSD who was also affected with demyelinating neuropathy.
Anti-aquaporin 4 antibodies or other undetermined humoral factors may have caused peripheral
neuropathy. Further investigation of the pathogenesis of peripheral neuropathy with NMOSD is
needed.
Journal of Multiple Sclerosis 9(2):24-27, 2018